MME Calculation Formula:
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MME (Morphine Milligram Equivalent) per day is a standardized measurement used to compare the relative potency of different opioid medications. It helps healthcare providers assess opioid dosing and monitor for potential overdose risk.
The calculator uses the MME calculation formula:
Where:
Explanation: The formula converts any opioid dose to its equivalent in morphine milligrams, allowing for standardized comparison across different opioid medications.
Details: Calculating MME is crucial for opioid risk assessment, medication management, and preventing opioid misuse. Higher MME values are associated with increased risk of overdose and adverse effects.
Tips: Enter the opioid dose in milligrams, the specific opioid conversion factor, and the dosing interval in hours. All values must be valid positive numbers.
Q1: What are common opioid conversion factors?
A: Common factors include: Morphine (1), Oxycodone (1.5), Hydrocodone (1), Hydromorphone (4), Fentanyl (varies by formulation).
Q2: Why is MME monitoring important?
A: MME helps identify patients at high risk for overdose and guides safe opioid prescribing practices according to clinical guidelines.
Q3: What MME level is considered high risk?
A: Generally, MME ≥50 mg/day increases overdose risk, and ≥90 mg/day significantly increases risk. Individual patient factors should also be considered.
Q4: Are there limitations to MME calculations?
A: Yes, MME doesn't account for individual metabolism, tolerance, or drug interactions. It should be used as a guide alongside clinical judgment.
Q5: How often should MME be calculated?
A: MME should be calculated at each opioid prescription, dose change, or when adding new opioid medications to a patient's regimen.